Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts

Table 1 Subject Characteristics

	Asthmatic Subjects	Healthy Subjects	P Value
	n = 11	n = 10
Age yrs. (mean ± SD)	12.3 (3.3)	11.3 (3.4)	0.5
Sex (female/male)	2/9	6/4
Currently using inhaled steroids (%)	9 (82%)
History of atopy, n; (%)	10 (91%)
Positive RAST, n; (%)	10 (91%)
IgE IU/mL (median ± SD)	890 (1536)	20.9 (13.1)	0.005
FVC % predicted (mean ± SD)	99.7 (11.2)	99.8 (13.8)	0.98
FEV₁/FVC Ratio (mean ± SD)	0.82 (0.05)	0.89 (0.04)	0.005
FEV₁% predicted (mean ± SD)	89.9 (8.2)	100.7 (15.4)	0.24
FEF_25–75% predicted (mean ± SD)	85.0 (20.4)	104.1 (15.4)	0.08
FENO ppb (mean ± SD)	28.3 (41.1)	9.3 (4.6)	0.15

RAST Radioallergosorbent testing, FVC Forced vital capacity, FEV₁ Forced expiratory volume in 1 s, FEF_25–75 Forced expiratory flow between 25 and 75% of expiration

ISSN: 1465-993X