Fig. 3
From: Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
Impact of OxLDL immunization on cigarette smoke-induced alterations in lung functions. Six to eight weeks old female BALB/c mice (n = 5/group) were injected with PBS alone or immunized against OxLDL (OxLDL:Addavax) and exposed to room air or cigarette smoke for 8 weeks. Pulmonary mechanics were assessed using the FlexiVent showing (a) inspiratory capacity (from deep inflation), b compliance (from Snap Shot 150), c resistance (from Snap Shot 150), d Newtonian resistance (from Quick Prime 3), e tissue damping (from Quick Prime 3), f tissue elastance (from Quick Prime 3) and g pressure-volume (P-V) loop. One-way ANOVA followed by Tukey’s multiple comparison tests *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; NS = not significantly different after two-sided Student T test