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Fig. 6 | Respiratory Research

Fig. 6

From: PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs

Fig. 6

The effect of PDGF-BB on TXB2 and 6-keto PGF1α. a TXB2-generation in dependence of the perfusion time. b Comparison of TXB2-generation within the groups at the same time. c 6-keto PGF1α-generation in dependence of the perfusion time. d Comparison of 6-keto PGF1α-generation within the groups at the same time. For all (□) control (n = 6); (■) perfusion with PDGF-BB (n = 6); (grey square) perfusion with imatinib / PDGF-BB (n = 6); (□) perfusion with imatinib (n = 6). a/c Statistics was performed by the Wilcoxon signed ranked test. b/d Statistics was performed by the Mann-Whitney U test. P < 0.05 are considered as significant: * p < 0.05 and ** p < 0.01

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