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Fig. 2 | Respiratory Research

Fig. 2

From: PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs

Fig. 2

IPL: Effect of PDGF-BB on the pulmonary vascular tone. a Effect of PDGF-BB on PPA. b Effect of PDGF-BB on Pcap. c Effect of PDGF-BB on Rpre. d Effect of PDGF-BB on Rpost. For all: (○) control (n = 7); (■) PDGF-BB (n = 7); (grey circle) imatinib (n = 7); (grey square) perfused imatinib / PDGF-BB (n = 7); (□) nebulised imatinib / PDGF-BB (n = 6); a-d Statistics was performed by a LMM. P < 0.05 are considered as significant: * p < 0.05, ** p < 0.01 and *** p < 0.001. a grey square / grey circle Time point 0 (§) vs. 140 (§§) min: p < 0.001. d grey circle Time point 0 (§) vs. 140 (§§) min: p < 0.05

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