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Table 3 Summary of logistic regression models relative to exacerbation with coefficient odds ratios, 95% confidence intervals and other model measures. Each column represents the regression coefficients for each of the 3 models

From: Circulating microRNAs and prediction of asthma exacerbation in childhood asthma

Variable

miR modela

Clinical model

miR + Clinical model

hsa-miR-206b

0.64**$ (0.45,0.89)

__

0.65** (0.44, 0.92)

hsa-miR-146b

0.72** (0.52,0.98)

__

0.67** (0.47,0.93)

hsa-miR-720

0.75 (0.51, 1.1)

__

0.70* (0.46,1.03)

Clinical score

__

1.36*** (1.14,1.64)

1.38*** (1.15,1.69)

Age

__

1.01 (0.84,1.23)

0.97 (0.80,1.20)

Sex

__

0.79 (0.36,1.73)

0.70 (0.29,1.65)

Observations

153

153

153

Log Likelihood

−76.8

−79.5

−69.9

Akaike Information Criterion (AIC)

161.6

167

153.7

Hosmer-Lemeshow Goodness of Fit Test^

Χ2 = 9.15

p-value = 0.33

Χ2 = 8.45

p-value = 0.39

Χ2 = 7.07

p-value = 0.53

  1. aThe miRNA model was determined by backwards stepwise selection. The clinical score model was adjusted for age and sex per original publication
  2. bEach of the model coefficients presents the odds ratio and the 95% confidence interval in parenthesis
  3. P-values are marked by an asterisk (*) with: *p < 0.1, **p < 0.05, ***p < 0.01
  4. ^10 bins used to calculate quantiles with degree of freedom = 8