Circulating microRNAs and prediction of asthma exacerbation in childhood asthma

Respiratory Research

Table 2 Univariate (unadjusted) logistic regression model for microRNAs relative to exacerbation with missing cycle threshold values replaced by its sample-wise cycle threshold value median

microRNA	Odds ratio (OR)	95% Confidence Interval (CI)	p-value
miR-206^c	0.60	0.42–0.83	0.004
miR-146b-5p^c	0.66	0.48–0.89	0.007
miR-222-3p	0.70	0.52–0.93	0.02
miR-409-3p^c	0.73	0.56–0.95	0.02
miR-223-5p^b	0.62	0.40-0.92	0.02
miR-126-5p^c	0.68	0.48–0.93	0.03
miR-339-3p^b	0.72	0.53-0.96	0.03
miR-30e-3p	0.70	0.49–0.95	0.03
miR-126-3p	0.74	0.56–0.96	0.03
miR-342-3p^c	0.80	0.64–0.98	0.04
miR-454-3p^a	0.77	0.60-0.98	0.04
miR-720	0.71	0.50–0.98	0.046

^amiRNA previously reported to be associated with baseline ^bFVC% and baseline ^cFEV1/FVC [26]

ISSN: 1465-993X