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Table 1 Correlation between expression of circRNA_0046264 and clinic pathological features in lung cancer patients

From: Hsa_circ_0046264 up-regulated BRCA2 to suppress lung cancer through targeting hsa-miR-1245

Parameters

Group

Total

circRNA_0046264

P

High

Low

Age

≤ 60

46

24

22

0.528

>60

53

31

22

 

Gender

Female

23

12

11

0.710

Male

76

43

33

 

Tumor diameter

≤5 cm

41

25

16

0.362

>5 cm

58

30

28

 

Staging

I

56

38

18

0.0003b

II

10

7

3

 

III

12

4

8

 

IV

21

6

15

 

Tumor differentiation

well

7

5

2

0.111

moderate

73

36

37

 

poor

19

14

5

 

Pathological type

Squamous cell carcinoma

36

17

19

0.207

Adenocarcinoma

63

38

25

 

Lymphatic metastasis

Yes

23

7

16

0.006b

No

76

48

28

 
  1. aLow and High expression group were divided according to the median ratio of relative circRNA_0046264 expression
  2. bP value was determined by chi-square analysis. P<0.05 was statistically significant