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Table 3 Multivariate regression analysis for the relationship between bilirubin and pulmonary lung function

From: Association of serum bilirubin level with lung function decline: a Korean community-based cohort study

Lung function parameters Bilirubin Bilirubin category
Quintile 1 Quintile 2 Quintile 3 Quintile 4 Quintile 5
FEV1, L
Estimated mean (SE) 0.12(0.02) ref 0.03(0.02) 0.06(0.02) 0.07(0.02) 0.11(0.02)
P-value < 0.001   0.154 0.002 < 0.001 < 0.001
FVC, L
Estimated mean (SE) 0.14(0.02) ref 0.05(0.02) 0.10(0.02) 0.09(0.02) 0.13(0.02)
P-value < 0.001   0.018 < 0.001 < 0.001 < 0.001
FEV1/FVC, %
Estimated mean (SE) 0.51(0.27) ref −0.39(0.25) −0.47(0.25) 0.22(0.25) 0.26(0.25)
P-value 0.059   0.113 0.055 0.371 0.307
FEF25–75%, L/s
Estimated mean (SE) 0.15(0.04) ref 0.01(0.05) 0.03(0.05) 0.11(0.05) 0.20(0.05)
P-value < 0.001   0.857 0.575 0.022 < 0.001
  1. Notes: Data were adjusted for age, sex, body mass index, and smoking status (current smoker, former smoker, and never-smoker)
  2. Abbreviations: SE standard error, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, FEF 25–75% forced expiratory flow between 25 and 75% of vital capacity