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Fig. 7 | Respiratory Research

Fig. 7

From: Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma

Fig. 7

Disruption of coordinated response to allergic asthma in hypoargininemic and control mice. The correlation of parameters of lung function, plasma concentration of arginine, abundance of pulmonary mRNAs and proteins, and pulmonary histopathology were compared in control and asthmatic F/A2tg/tg and wild-type littermate mice. Correlation coefficients of parameters indicated above and to the left of the columns and rows, respectively, are shown for F/A2wt/wt (upper right triangle) and F/A2tg/tg mice (lower left triangle). n = 15 or 16 PBS/OVA- and OVA/OVA-treated mice of both genotypes. The significance of the correlations is color-coded according to the P-value of the correlation coefficient (Spearman’s rho): yellow: 0.05 > P > 0.01, orange: 0.01 > P > 0.001, and red: P < 0.001

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