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Table 1 Characteristics of subjects included in the exhaled breath condensate (EBC) study

From: The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD

 

Healthy Non-smokers

Asthma

COPD

Number of subjects

16

23

25

Sex (M/F)

11/5

11/12

11/14

Age (years)

56.75 ± 2.71

54.22 ± 3.05

66.96 ± 1.76ll**

Pack-years

0

0

39.10±3.70

Time since diagnosis (years)

10.13 ± 2.34

4.46 ± 0.84

PB FEV1% of predicted (%)

107.90 ± 3.23

82.59 ± 4.56

62.32 ± 2.76*†

PB FEV1/FVC (%)

76.32 ± 1.46

68.14 ± 2.38

54.03 ± 1.89*†

Current smokers (%)

0

0

32

Use of ICS (%)

0

0

0

Atopic subjects (%)

0

56.52

0

Blood eosinophil number (cells/μl)

181 ± 35

315 ± 35§

242 ± 31

Blood eosinophil percentage (%)

3.01 ± 0.54

4.74 ± 0.59§

3.16 ± 0.41

  1. PB post bronchodilator, FEV 1 forced expiratory volume in first second, FVC forced vital capacity, ICS inhaled corticosteroids
  2. *COPD vs Asthma p < 0.001; COPD vs Healthy Non-smokers p < 0.001; COPD vs Asthma p < 0.01; §Asthma vs Healthy Non-smokers p < 0.05; llCOPD vs Healthy Non-smokers p < 0.05; **COPD vs Asthma p < 0.01