Fig. 3
From: Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
Normal lung fibroblasts were pre-treated with/without the FAK inhibitor PF573228 (10 μM) or the PI3K inhibitor LY294002 (10 μM) for one hour prior to treatment with TGF-β1 (10 ng/ml). Fas expression was then assessed by (a) qPCR; * p < 0.05 compared to untreated controls, n = 2 independent experimental replicates, (b) Western blot of whole cell lysates; representative blot with densitometry from three independent experimental replicates. * p < 0.05 and ** p < 0.01 compared to untreated controls