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Table 1 Differential metabolites between PAH model and controls

From: Metabolic reprogramming of the urea cycle pathway in experimental pulmonary arterial hypertension rats induced by monocrotaline

Name of metabolites

Category

Fold change

P value

VIP

AMP

Nucleotides

0.033

1.76E-05

2.127

urea

Organic acids

1.407

0.007

2.108

O-acetylcarnitine

lipid

1.321

0.007

1.859

cytosine

Organic compounds

1.643

0.007

2.004

2′-dexycytidine

Nucleosides

1.606

0.007

1.880

indole

Organic carbonic acids

1.438

0.013

1.658

betaine

Organic acids

1.408

0.014

1.625

p-hydroxybenzoate

others

1.417

0.019

1.830

N-acetylornithine

Organic acids

1.401

0.019

1.816

ornithine

Organic acids

1.417

0.036

1.790

4-hydroxy-L-proline

Organic acids

1.374

0.038

1.357

dc-SMA

others

1.734

0.051

1.492

phenylacetylglycine

Organic acids

3.2318

0.053

1.777

  1. VIP variable importance in projection, AMP adenosine monophosphate