Fig. 2From: Metabolic reprogramming of the urea cycle pathway in experimental pulmonary arterial hypertension rats induced by monocrotalineIncreased pulmonary vascular remodeling in MCT induced rats. (a) Representative micrographs of histological assessment demonstrating thickening of the pulmonary vascular (black arrow) in the PAH model group; (b) Representative micrographs of Immunostaining of lung-tissue-treated rats revealing increasing α-SMA expression in the distal pulmonary arteries (MCT, n = 5; Vehicle, n = 5). α-SMA = α-smooth muscle actin; MCT = monocrotaline (**P < 0.01)Back to article page