Table 5 Correlations between immunohistological findings and lung function parameters (n = 33)
From: Immunohistological features related to functional impairment in lymphangioleiomyomatosis
| Â | Density of nodules | Density of cysts | VEGF-D | MMP-9 | mTOR | D2-40 |
|---|---|---|---|---|---|---|
FEV1 (%predicted) | r = −0.51 p = 0.003 | r = −0.58 p < 0.001 | r = − 0.60 p < 0.001 | r = − 0.62 p < 0.001 | r = − 0.55 p = 0.002 | ns |
DLco (%predicted) | r = − 0.68 p < 0.001 | r = − 0.53 p = 0.003 | r = − 0.51 p = 0.004 | r = − 0.66 p < 0.001 | ns | r = − 0.48 p = 0.008 |