Group | Estimate | % change | 95% CI | p-value |
---|
NORMAL | −0.0039 | −0.90 | −1.26 - -0.54 |
0.0001
|
CF | −0.0045 | −1.04 | −2.21 - 0.16 | 0.090 |
COPD | 0.015 | 3.41 | 1.36 - 5.49 |
0.0016
|
cHP | −0.0024 | − 0.55 | −4.98 - 4.10 | 0.81 |
BOS | −0.0033 | −0.76 | −1.41 - -1.41 |
0.022
|
RAS | −0.0021 | −0.47 | − 0.88 - -0.06 |
0.027
|
- Mixed linear models were used to measure the association between tissue RTL and lung age, with the lung as random effect, adjusted for sex and BMI. Estimates are presented as percentage change (95% CI) in average RTL for each 1-year increase in lung age
- RTL relative telomere length, 95% CI 95% confidence interval, CF cystic fibrosis, COPD chronic obstructive pulmonary disease, cHP chronic hypersensitivity pneumonitis, BOS bronchiolitis obliterans syndrome, RAS restrictive allograft syndrome
- p-value < 0.05 is captured in bold