Fig. 2

Immunolocalization of NTPDase1/CD39 in Human Lung Structures: Parenchyma (a–d), Bronchi (e–h), and Pulmonary Arteries (i–l). CD39 was downregulated in lung parenchyma, bronchial epithelial cells, and endothelial cells of pulmonary arteries in the COPD group. Images are of representative histological slides from the COPD (n = 15), NOS (n = 13), and NS (n = 12) groups. The primary antibody was omitted in the control experiments in images D, H, and L. Scale bars = 100 μm. Abbreviations: NTPDase1, nucleoside triphosphate diphosphohydrolase-1; COPD, Chronic obstructive pulmonary disease; NOS, Non-obstructed smokers; NS, Never smoker