Skip to main content

Advertisement

Table 1 Baseline characteristics of subjects with steady-state bronchiectasis and healthy controls

From: Arterial stiffness in adults with steady-state bronchiectasis: association with clinical indices and disease severity

  Bronchiectasis Controls P values
Age, y 51.0 ± 13.9 49.5 ± 11.9 0.47
Male sex, No. (%) 22 (27.5) 22 (27.5) 1.00
Body-mass index, kg/m2 20.5 ± 2.0 25.2 ± 3.6 < 0.001
Current smoking, No. (%) 12 (15.0%) 18 (22.5%) 0.22
SBP, mmHg 120.9 ± 9.6 117.6 ± 11.2 0.62
DBP, mmHg 81.6 ± 8.6 73.4 ± 10.5 0.34
HR, bpm 82.6 ± 5.3 80.1 ± 4.2 0.001
Spirometry
 FVC% predicted 82.3 ± 16.7
 FEV1% predicted 67.3 ± 21.4
mMRC grade 1.0 (0–2.0)
Exacerbation frequency in the past 12 mo 2.0 (1.3–5.0)
Hospital admission in the past 24 mo 2.0 (1.0–3.0)
Modiffied Reiff score for chest HRCT scan 5.0 (2.0–10.0)
PA colonization, No. (%) 17 (21.3%)
Aetiology
 Idiopathic, No. (%) 26 (32.5%)
 Post infective, No. (%) 25 (31.3%)
 COPD, No. (%) 14 (17.5%)
 Asthma, No. (%) 5 (6.3%)
 Othersa, No. (%) 10 (12.5%)
BSI Scores
 Mild (0–4), No. (%) 27 (33.8%)
 Moderate (5–8), No. (%) 11 (13.8%)
 Severe (≥9), No. (%) 42 (52.5%)
Comorbidities
 Hypertension, No. (%) 1 (1.3%) 2 (2.5%) 0.56
 Diabetes, No. (%) 6 (7.5%) 3 (3.8%) 0.30
 Coronary heart disease, No. (%) 3 (3.8%) 3 (3.8%) 1.00
 Stroke, No. (%) 0 (0%) 0 (0%)
 Peripheral arterial disease, No. (%) 0 (0%) 0 (0%)
Clinical chemistry
 Cholesterol, mmol/L 3.8 ± 1.1
 Triglyceride, mmol/L 1.0 ± 0.7
 LDL-C, mmol/L 2.2 (1.9–2.4)
 HDL-C, mmol/L 1.9 (1.0–1.4)
Systemic inflammatory markers
 IL-6, pg/mL 3.3 (1.8–7.9)
 IL-8, pg/mL 7.1 (4.3–11.8)
 C-reactive protein, mg/dL 1.17 (0.3–3.9)
 Fibrinogen, g/L 3.2 ± 0.9
  1. Data are depicted as mean ± SD, median (interquartile range [IQR]) or n (%)
  2. BSI bronchiectasis severity index, COPD chronic obstructive pulmonary disease, DBP diastolic blood pressure, FEV 1 forced expiratory volume in one second, FVC forced vital capacity, HR heart rate, HRCT high-resolution computed tomography, IL interleukin, mo month, mMRC modified Medical Research Council, PA Pseudomonas aeruginosa, SBP systolic blood pressure; y = year
  3. aAspiration (n = 2), Allergic Bronchopulmonary Aspergillosis (n = 3), Microscopic Polyangiitis (n = 1), Rheumatoid Arthritis (n = 1), Inflammatory Bowel Disease (n = 1), Kartagener’s Syndrome (n = 1), Primary Immunodeficiency (n = 1)