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Table 1 Baseline patient characteristics

From: Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation

   Sub-cohorts used for:
Main cohort
N = 122a
CCSP & SP-D
N = 19a
Inflammatory proteins
N = 15
Cell count
N = 6
Recipient age at transplant, year (Mean ± SD) 54.1 ± 16.7 55.3 ± 15.8 57.7 ± 11 56.7 ± 16.7
Primary diagnosis
 Idiopathic pulmonary fibrosis 53 (43.4%) 10 (52.6%) 7 (46.7%) 5(83.3%)
 Chronic obstructive pulmonary disease 23 (18.9%) 3 (15.8%) 4 (26.7%) 0
 Cystic fibrosis 16 (13.1%) 3 (15.8%) 3 (20%) 0
 Scleroderma 6 (4.9%) 1 (5.3%) 0 0
 Chronic Lung Allograft Dysfunction 5 (4.1%) 0 0 0
 Sarcoidosis 4 (3.3%) 0 0 0
 Bronchiectasis 4 (3.3%) 0 1 (6.7%) 0
 Alpha-1 antitrypsin deficiency 3 (2.5%) 0 0 0
 Langerhans cell histiocytosis 2 (1.6%) 1 (5.3%) 0 0
 Other 6 (4.9%) 1 (5.3%) 0 1 (16.7%)
Transplant type
 Single lung transplantation 23 (18.9%) 5 (26.3%) 5 (33.3%) 1 (16.7%)
 Bilateral lung transplantation 99 (81.1%) 14 (73.7%) 10 (66.7%) 5 (83.3%)
Male Gender 69 (56.6%) 14 (73.7%) 9 (60%) 3 (50%)
Number of lung transplants
 First lung transplant 116 (95.1%) 18 (94.7%) 15 (100%) 5 (83.3%)
 Second lung transplant 6 (4.9%) 1 (5.3%) 0 1 (16.7%)
CLAD status at time of bronchoscopy
 CLAD 14 (11.5%) 7 (36.8%) 3 (20%) 1 (16.7%)
 No CLAD 108 (88.5%) 12 (63.2%) 12 (80%) 5 (83.3%)
  1. AR=Acute rejection; n=number; %=percent of samples
  2. aNumber of patients is smaller than number of bronchoscopies