Table 1 Baseline patient characteristics
| Â | Â | Sub-cohorts used for: | ||
|---|---|---|---|---|
Main cohort N = 122a | CCSP & SP-D N = 19a | Inflammatory proteins N = 15 | Cell count N = 6 | |
Recipient age at transplant, year (Mean ± SD) | 54.1 ± 16.7 | 55.3 ± 15.8 | 57.7 ± 11 | 56.7 ± 16.7 |
Primary diagnosis | ||||
 Idiopathic pulmonary fibrosis | 53 (43.4%) | 10 (52.6%) | 7 (46.7%) | 5(83.3%) |
 Chronic obstructive pulmonary disease | 23 (18.9%) | 3 (15.8%) | 4 (26.7%) | 0 |
 Cystic fibrosis | 16 (13.1%) | 3 (15.8%) | 3 (20%) | 0 |
 Scleroderma | 6 (4.9%) | 1 (5.3%) | 0 | 0 |
 Chronic Lung Allograft Dysfunction | 5 (4.1%) | 0 | 0 | 0 |
 Sarcoidosis | 4 (3.3%) | 0 | 0 | 0 |
 Bronchiectasis | 4 (3.3%) | 0 | 1 (6.7%) | 0 |
 Alpha-1 antitrypsin deficiency | 3 (2.5%) | 0 | 0 | 0 |
 Langerhans cell histiocytosis | 2 (1.6%) | 1 (5.3%) | 0 | 0 |
 Other | 6 (4.9%) | 1 (5.3%) | 0 | 1 (16.7%) |
Transplant type | ||||
 Single lung transplantation | 23 (18.9%) | 5 (26.3%) | 5 (33.3%) | 1 (16.7%) |
 Bilateral lung transplantation | 99 (81.1%) | 14 (73.7%) | 10 (66.7%) | 5 (83.3%) |
Male Gender | 69 (56.6%) | 14 (73.7%) | 9 (60%) | 3 (50%) |
Number of lung transplants | ||||
 First lung transplant | 116 (95.1%) | 18 (94.7%) | 15 (100%) | 5 (83.3%) |
 Second lung transplant | 6 (4.9%) | 1 (5.3%) | 0 | 1 (16.7%) |
CLAD status at time of bronchoscopy | ||||
 CLAD | 14 (11.5%) | 7 (36.8%) | 3 (20%) | 1 (16.7%) |
 No CLAD | 108 (88.5%) | 12 (63.2%) | 12 (80%) | 5 (83.3%) |