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Fig. 2 | Respiratory Research

Fig. 2

From: Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes

Fig. 2

Effect of acute E-cigarette aerosol inhalation on small airway epithelium genome-wide transcriptome profiles. a Volcano plot showing expression of all genes comparing baseline to post-EC exposure visit from SAE of never-smokers who were exposed to acute inhalation of EC with nicotine (n = 7 subjects). Significance determined by p value < 0.05 (horizontal dashed line) and fold-change of post-EC exposure to baseline > 1.5 (vertical dashed lines). b Hierarchical clustering of differentially expressed genes from SAE of never-smokers who were exposed to acute inhalation of EC with nicotine (n = 7 subjects). c Volcano plot showing expression of all genes comparing baseline to post-EC exposure visit from SAE of never-smokers who were exposed to acute inhalation of EC without nicotine (n = 3 subjects). Significance determined by p value < 0.05 (horizontal dashed line) and fold-change of post-EC exposure to baseline > 1.5 (vertical dashed lines). d Hierarchical clustering of differentially expressed genes from SAE of never-smokers who were exposed to acute inhalation of EC without nicotine (n = 3 subjects)

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