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Fig. 3 | Respiratory Research

Fig. 3

From: Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung

Fig. 3

Small-size pulmonary arteries from Control (a and b) and Antimycin Day 12 (c and d) and Antimycin Day-24 (e, f, g, h) rats. Asterisks indicate vasoconstriction and arrows denote the presence of perivascular cuff indicative of endothelial barrier dysfunction. H&E staining: a and e; Verhoeff-Van Gieson (VVG) staining: b, f-j; Pentachrome staining c and d. Photomicrographs are representative of 5 lung preparations per experimental group. Scale bar indicate 200 μm for a, b, and h and 100 μm for c, d, e, f, and g. Quantification of perivascular edema area showed a significant decrease in both small (i) and large (j) pulmonary arteries in day 24 group compared with day 12. Data are mean values ± SEM, N = 9–17 per group. *P < 0.05 vs. AA 12 days using unpaired t-test

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Respiratory Research

ISSN: 1465-993X

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