Table 2 Linear regression analysis of biomarker levels 2005 in relation to lung function decline, in non-COPD and COPD respectively
From: Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort
Change in: | non-COPD | COPD | ||
|---|---|---|---|---|
ml FEV1 | Beta | P | Beta | P |
MMP-9 | −0.098 | 0.016 | −0.063 | 0.240 |
TIMP-1 | 0.100 | 0.014 | 0.025 | 0.648 |
MMP-9/TIMP-1 ratio | −0.128 | 0.002 | −0.072 | 0.183 |
units of FEV1 percent predicted value | ||||
MMP-9 | −0.117 | 0.004 | −0.091 | 0.089 |
TIMP-1 | 0.056 | 0.169 | 0.009 | 0.864 |
MMP-9/TIMP-1-ratio | −0.109 | 0.007 | −0.086 | 0.110 |