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Fig. 2 | Respiratory Research

Fig. 2

From: Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways

Fig. 2

Graphical representation of Unified Theory analysis for BDP/FF combination administered at 100:6 concentration-ratio reporting the logarithmic Combination Index plot (a and b) and the normalized isobologram (c and d) in non-sensitized (a and c) and passively sensitized (b and d) human medium bronchi submaximally contracted by histamine. Points represent the mean ± SEM of n = 5 sub-segmental bronchi from different subjects; the labels of points report the weight/weight ratio (ng/ng) between BDP and FF. BDP: beclomethasone dipropionate; CI: Combination Index; Fa: fraction affected; FF: formoterol fumarate. Fu: fraction unaffected

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