Skip to main content

Table 4 Hemodynamic parameters. All the groups were statistically compared by ANOVA followed by Tukey’s multiple comparison

From: Crocin attenuates cigarette smoke-induced lung injury and cardiac dysfunction by anti-oxidative effects: the role of Nrf2 antioxidant system in preventing oxidative stress

Parameters Control Crocin COPD COPD + Crocin
LVDP (mmHg) 79.66 ± 7.31 83.61 ± 6.56 86.82 ± 3.74 82.37 ± 6.60
LVEDP (mmHg) 7.58 ± 0.46 7.63 ± 0.36 8.03 ± 0.25 7.75 ± 0.35
LVSP (mmHg) 87.25 ± 7.28 91.25 ± 6.67 95.37 ± 4.17 89 ± 5.78
dp/dt max (mmHg) 2864.25 ± 141.54 2934.25 ± 71.22 3078.87 ± 93.48* 2900.75 ± 144.72
dp/dt min (mmHg) − 2987.87 ± 147.05 − 3016 ± 118.03 − 3052.25 ± 84.74 − 3011.50 ± 92.42
RPP (mmHg/min) 22,195.12 ± 3120 24,103.75 ± 3201 27,518.75 ± 1227** 23,406.06 ± 3351
Perfusion pressure (mmHg) 63.25 ± 5.11 64 ± 4.44 59.12 ± 6.46 61 ± 7.92
HR (bpm) 259 ± 16.93 263 ± 18.49 280 ± 21.61* 262 ± 21.76
  1. *P < 0.05 and **P < 0.01 vs. Control, P < 0.05 vs. COPD. Data are expressed as the mean + SEM, n = 8