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Fig. 8 | Respiratory Research

Fig. 8

From: Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

Fig. 8

Investigation of the functional activity of MATE1 and P-gp in THP-1 cells using transporter inhibitors. Uptake in differentiated THP-1 cells 72 h after PMA induction overnight. a Metformin (11 μM) uptake with (◊) and without (●) pyrimethamine (1 μM) in the incubation and (b) digoxin (0.5 μM) uptake with (◊) and without (●) elacridar (10 μM) in the incubation. Results are given as mean ± S.D., n = 5 to 6 for each time point. *** p < 0.001

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Respiratory Research

ISSN: 1465-993X

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