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Fig. 3 | Respiratory Research

Fig. 3

From: Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals

Fig. 3

MATE1 protein expression in airway epithelial cells, alveolar macrophages and infiltrating T-cells. Paraffin sections of human lung tissue from healthy individuals (left column) and ex-smokers with COPD (right column) were immunostained with anti-MATE1 antibody (brown) and counterstained with hematoxylin (blue). a and b Show apical staining in bronchial epithelial cells and in c and d bronchiolar epithelium (arrow heads) as well as staining in some inflammatory cells migrating through the bronchial and bronchiolar epithelium (arrows). e and f Show strong expression of MATE1 in alveolar macrophages in the peripheral tissue (arrows). g and h Show co-staining of MATE1 antibody with T cell (CD3) and B cell (CD20) marker antibodies demonstrating that the infiltrating T cells (arrows) but not B cells are MATE1 positive. Scale bar: 20 μm

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