Fig. 6

Receptor-mediated inhibition of TGFβ-mediated FMT. Concentration effect curves for the inhibition of FMT were determined in HLF following exposure to a range of agonists targeting the (a) IP or EP receptors, (b) β₂ adrenoceptor, (c) other GPCR and (d) non-receptors, in the presence of an EC₈₀ concentration of TGFβ for 48 h. For each individual experiment, data were normalised to the maximal levels of FMT observed with TGFβ, and are expressed as means ± SEM for 4 independent experiments