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Fig. 5 | Respiratory Research

Fig. 5

From: The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

Fig. 5

Receptor-mediated inhibition of PDGF-mediated proliferation. Concentration effect curves for the inhibition of proliferation were determined in HLF following exposure to a range of agonists targeting the (a) IP receptor, (b) EP receptor, (c) β2 adrenoceptor, (d) other GPCR and (e) non-receptors, in the presence of an EC80 concentration of PDGF for 24 h. For each individual experiment, data were normalised to the maximal proliferation observed with PDGF, and are expressed as means ± SEM for at least 3 independent experiments

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