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Fig. 3 | Respiratory Research

Fig. 3

From: The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

Fig. 3

a The effects of dopamine (1 μM) or the dopamine D1 receptor agonists (A68930 or SKF38393; 1 μM respectively) on cAMP production in cultured (i) 16HBE14o- cells and (ii) NCI-H292 cells. n = 6. b The effect of dopamine D1-like receptor selective antagonists SCH23390 or SCH39166 on A68930-stimulated cAMP production in cultured (i) 16HBE14o- cells and (ii) NCI-H292 cells. Cells were pretreated with SCH23390 (1 μM) or SCH39166 (1 μM) for 30 min prior to A68930 (1 μM) treatment for 20 min. n = 6. Data represent means ± SEM. **P < 0.01 and ***P < 0.001 compared with basal. #P < 0.05 and ###P < 0.001 compared with A68930 alone

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