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Table 3 Functional, analytic, microbiologic, and radiological characteristics of subjects with asthma, with and without bronchiectasis

From: Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: a study in 398 patients

Parameter Whole group
(n = 398)
Asthma with bronchiectasis
(n = 113)
Asthma without bronchiectasis
(n = 285)
P value
FEV1, % Post-BD (m ± sd) 80 ± 22.9 77 ± 22 81 ± 23 0.061
FEV1, (ml) Post-BD (m ± sd) 1989 ± 829 1792 ± 785 2066 ± 834 0.002
FVC, % Post-BD (m ± sd) 93 ± 20 90 ± 17 94 ± 20 0.054
FVC, (ml) Post-BD (m ± sd) 2790 ± 1022 2542 ± 963 2888 ± 1029 0.002
FEV1/FVC ratio Post-BD (m ± sd) 69 ± 11 68.9 ± 11 69.8 ± 11 ns
Classification by FEV1% ns
  > 80%, n (%) 189 (47.59) 45 (39.8) 144 (50.5)  
 50- < 80%, n (%) 179 (45) 56 (49.6) 123 (43.2)  
  < 50%, n (%) 30 (7.5) 12 (10.6) 18 (6.3)  
FeNO, ppb (m ± sd) 29.9 ± 29.9 23.9 ± 23 32.3 ± 32 0.039
Eosinophils, cells/μL (m ± sd) 310 ± 254 324 ± 288 304 ± 239 ns
IgE, IU/mL (m ± sd) 269 ± 541 205 ± 362 298 ± 609 ns
Positive sputum culture, n (%) 50 (24.2) 22 (29.7) 28 (21.1) ns
Air trapping measured by HRCT, n (%) 52 (13) 25 (22.1) 27 (9.5) 0.002
  1. Data are presented as n (number) and (%) for qualitative variables and mean (standard deviation) for quantitative variables; ns not significant, FEV 1 Forced expiratory volume in one second, post-BD Post-bronchodilator, FVC Forced vital capacity, FeNO Fractional exhaled nitric oxide, ppb parts per billion