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Table 2 Baseline and clinical characteristics of subjects with asthma, with and without bronchiectasis

From: Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: a study in 398 patients

Parameter Whole group
(n = 398)
Asthma with bronchiectasis
(n = 113)
Asthma without bronchiectasis
(n = 285)
P value
Age, years (m ± sd) 57.06 ± 15.6 59.83 ± 13.8 55.96 ± 16.1 0.017
Female gender, n (%) 281 (70.6) 87 (77) 194 (68.1) ns
BMI (m ± sd) 28.77 ± 5.3 29.04 ± 5.4 28.7 ± 5.2 ns
Dyspnea MRC, ns
 Score 0–2, n (%) 370 (93.7) 102 (91.9) 268 (94.4)  
 Score 3–4, n (%) 25 (6.3) 9 (8.1) 16 (5.6)  
 Packs/yr smoked (m ± sd) 1.54 ± 2.85 1.29 ± 2.62 1.64 ± 2.93 ns
 Never smoked, n (%) 283 (71.1) 85 (75.2) 198 (69.5) ns
Asthma by severity: 0.005
 Moderate Asthma, n (%) 160 (40.2) 33 (29.2) 127 (44.6)  
 Severe Asthma, n (%) 238 (59.8) 80 (70.8) 158 (55.4)  
 ACT (m ± sd) 15.36 ± 4.4 14.6 ± 4.7 15.7 ± 4.3 0.06
 Time from diagnosis of asthma in years (m ± sd) 16.8 ± 16 18.1 ± 16.6 16.3 ± 15.8 ns
 Previous pneumonia, n (%) 63 (15.8) 26 (23) 37 (13) 0.020
 Rhinitis, n (%) 239 (60.1) 62 (56.9) 177 (63.4) ns
 Nasal sinus polyps, n (%) 46 (11.7) 19 (17.1) 27 (27.8) 0.059
 GERD, n (%) 112 (28.3) 33 (29.5) 79 (27.8) ns
 Atopy, n (%) 203 (54.6) 52 (48.6) 151 (57) ns
 Corticoid-dependent, n (%) 25 (6.3) 9 (8) 16 (5.6) ns
 ED visits in the last year (m ± sd) 1.85 ± 2.99 2.34 ± 3.4 1.66 ± 2.8 0.042
 Hospitalizations in the last year (m ± sd) 0.13 ± 0.39 0.13 ± 0.39 0.12 ± 0.38 ns
 Moderate-severe exacerbations (m ± sd) 2 ± 2.84 2.54 ± 3.35 1.79 ± 2.59 0.034
 Cycles of oral corticoid therapy in the previous year (m ± sd) 1.1 ± 2.08 1.33 ± 2.33 1 ± 1.97 ns
 Cycles of antibiotic therapy in the previous year (m ± sd) 1.35 ± 1.85 1.83 ± 2 1.16 ± 1.7 0.002
 Chronic expectoration, n (%) 82 (20.6) 36 (31.9) 46 (16.1) 0.001
 Purulent sputum, n (%) 16 (4) 9 (8) 7 (2.5) 0.020
 Charlson Index (m ± sd) 3.18 ± 2.12 3.36 ± 1.8 3.1 ± 2.2 ns
  1. Data are presented as n (number) and (%) for qualitative variables and mean (standard deviation) for quantitative variables
  2. MRC Medical Research Council, ns not significant, BMI Body Mass Index, ACT Asthma control test, GERD Gastroesophageal reflux disease