Parameter | Whole group (n = 398) | Asthma with bronchiectasis (n = 113) | Asthma without bronchiectasis (n = 285) | P value |
---|---|---|---|---|
Age, years (m ± sd) | 57.06 ± 15.6 | 59.83 ± 13.8 | 55.96 ± 16.1 | 0.017 |
Female gender, n (%) | 281 (70.6) | 87 (77) | 194 (68.1) | ns |
BMI (m ± sd) | 28.77 ± 5.3 | 29.04 ± 5.4 | 28.7 ± 5.2 | ns |
Dyspnea MRC, | ns | |||
Score 0–2, n (%) | 370 (93.7) | 102 (91.9) | 268 (94.4) | |
Score 3–4, n (%) | 25 (6.3) | 9 (8.1) | 16 (5.6) | |
Packs/yr smoked (m ± sd) | 1.54 ± 2.85 | 1.29 ± 2.62 | 1.64 ± 2.93 | ns |
Never smoked, n (%) | 283 (71.1) | 85 (75.2) | 198 (69.5) | ns |
Asthma by severity: | 0.005 | |||
Moderate Asthma, n (%) | 160 (40.2) | 33 (29.2) | 127 (44.6) | |
Severe Asthma, n (%) | 238 (59.8) | 80 (70.8) | 158 (55.4) | |
ACT (m ± sd) | 15.36 ± 4.4 | 14.6 ± 4.7 | 15.7 ± 4.3 | 0.06 |
Time from diagnosis of asthma in years (m ± sd) | 16.8 ± 16 | 18.1 ± 16.6 | 16.3 ± 15.8 | ns |
Previous pneumonia, n (%) | 63 (15.8) | 26 (23) | 37 (13) | 0.020 |
Rhinitis, n (%) | 239 (60.1) | 62 (56.9) | 177 (63.4) | ns |
Nasal sinus polyps, n (%) | 46 (11.7) | 19 (17.1) | 27 (27.8) | 0.059 |
GERD, n (%) | 112 (28.3) | 33 (29.5) | 79 (27.8) | ns |
Atopy, n (%) | 203 (54.6) | 52 (48.6) | 151 (57) | ns |
Corticoid-dependent, n (%) | 25 (6.3) | 9 (8) | 16 (5.6) | ns |
ED visits in the last year (m ± sd) | 1.85 ± 2.99 | 2.34 ± 3.4 | 1.66 ± 2.8 | 0.042 |
Hospitalizations in the last year (m ± sd) | 0.13 ± 0.39 | 0.13 ± 0.39 | 0.12 ± 0.38 | ns |
Moderate-severe exacerbations (m ± sd) | 2 ± 2.84 | 2.54 ± 3.35 | 1.79 ± 2.59 | 0.034 |
Cycles of oral corticoid therapy in the previous year (m ± sd) | 1.1 ± 2.08 | 1.33 ± 2.33 | 1 ± 1.97 | ns |
Cycles of antibiotic therapy in the previous year (m ± sd) | 1.35 ± 1.85 | 1.83 ± 2 | 1.16 ± 1.7 | 0.002 |
Chronic expectoration, n (%) | 82 (20.6) | 36 (31.9) | 46 (16.1) | 0.001 |
Purulent sputum, n (%) | 16 (4) | 9 (8) | 7 (2.5) | 0.020 |
Charlson Index (m ± sd) | 3.18 ± 2.12 | 3.36 ± 1.8 | 3.1 ± 2.2 | ns |