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Table 2 Baseline and clinical characteristics of subjects with asthma, with and without bronchiectasis

From: Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: a study in 398 patients

Parameter

Whole group

(n = 398)

Asthma with bronchiectasis

(n = 113)

Asthma without bronchiectasis

(n = 285)

P value

Age, years (m ± sd)

57.06 ± 15.6

59.83 ± 13.8

55.96 ± 16.1

0.017

Female gender, n (%)

281 (70.6)

87 (77)

194 (68.1)

ns

BMI (m ± sd)

28.77 ± 5.3

29.04 ± 5.4

28.7 ± 5.2

ns

Dyspnea MRC,

ns

 Score 0–2, n (%)

370 (93.7)

102 (91.9)

268 (94.4)

 

 Score 3–4, n (%)

25 (6.3)

9 (8.1)

16 (5.6)

 

 Packs/yr smoked (m ± sd)

1.54 ± 2.85

1.29 ± 2.62

1.64 ± 2.93

ns

 Never smoked, n (%)

283 (71.1)

85 (75.2)

198 (69.5)

ns

Asthma by severity:

0.005

 Moderate Asthma, n (%)

160 (40.2)

33 (29.2)

127 (44.6)

 

 Severe Asthma, n (%)

238 (59.8)

80 (70.8)

158 (55.4)

 

 ACT (m ± sd)

15.36 ± 4.4

14.6 ± 4.7

15.7 ± 4.3

0.06

 Time from diagnosis of asthma in years (m ± sd)

16.8 ± 16

18.1 ± 16.6

16.3 ± 15.8

ns

 Previous pneumonia, n (%)

63 (15.8)

26 (23)

37 (13)

0.020

 Rhinitis, n (%)

239 (60.1)

62 (56.9)

177 (63.4)

ns

 Nasal sinus polyps, n (%)

46 (11.7)

19 (17.1)

27 (27.8)

0.059

 GERD, n (%)

112 (28.3)

33 (29.5)

79 (27.8)

ns

 Atopy, n (%)

203 (54.6)

52 (48.6)

151 (57)

ns

 Corticoid-dependent, n (%)

25 (6.3)

9 (8)

16 (5.6)

ns

 ED visits in the last year (m ± sd)

1.85 ± 2.99

2.34 ± 3.4

1.66 ± 2.8

0.042

 Hospitalizations in the last year (m ± sd)

0.13 ± 0.39

0.13 ± 0.39

0.12 ± 0.38

ns

 Moderate-severe exacerbations (m ± sd)

2 ± 2.84

2.54 ± 3.35

1.79 ± 2.59

0.034

 Cycles of oral corticoid therapy in the previous year (m ± sd)

1.1 ± 2.08

1.33 ± 2.33

1 ± 1.97

ns

 Cycles of antibiotic therapy in the previous year (m ± sd)

1.35 ± 1.85

1.83 ± 2

1.16 ± 1.7

0.002

 Chronic expectoration, n (%)

82 (20.6)

36 (31.9)

46 (16.1)

0.001

 Purulent sputum, n (%)

16 (4)

9 (8)

7 (2.5)

0.020

 Charlson Index (m ± sd)

3.18 ± 2.12

3.36 ± 1.8

3.1 ± 2.2

ns

  1. Data are presented as n (number) and (%) for qualitative variables and mean (standard deviation) for quantitative variables
  2. MRC Medical Research Council, ns not significant, BMI Body Mass Index, ACT Asthma control test, GERD Gastroesophageal reflux disease