Table 1 Demographic characteristics of individuals in the analysis of severe COPD
From: Integrative genomics identifies new genes associated with severe COPD and emphysema
| Â | COPDGene-NHW | COPDGene-AA | ECLIPSE | NETT/NAS | Norway GenKOLS | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Cases | Control Subjects | Cases | Control Subjects | Cases | Control Subjects | Cases | Control Subjects | Cases | Control Subjects | |
N | 1390 | 2534 | 352 | 1749 | 999 | 178 | 373 | 435 | 383 | 808 |
Age, years (SD) | 65.2 (7.8) | 59.5 (8.7) | 60.6 (8.1) | 52.8 (6.0) | 63.5 (7.0) | 57.5 (9.4) | 67.5 (5.8) | 69.8 (7.5) | 66.7 (9.7) | 55.6 (9.7) |
Smoking pack-years (SD) | 58.7 (28.4) | 37.8 (20.3) | 43.9 (23.4) | 36.4 (20.1) | 50.7 (26.3) | 32.1 (24.8) | 66.4 (30.7) | 40.7 (27.9) | 33.0 (19.9) | 19.7 (13.6) |
FEV1, % predicted (SD) | 34.0 (9.9) | 96.8 (11.0) | 34.8 (10.4) | 98.4 (12.2) | 36.5 (8.6) | 107.8 (13.6) | 28.1 (7.4) | 100.0 (13.2) | 34.4 (10.3) | 94.9 (9.2) |
FEV1/FVC (SD) | 0.390 (0.103) | 0.779 (0.050) | 0.430 (0.105) | 0.800 (0.052) | 0.387 (0.095) | 0.790 (0.053) | 0.324 (0.064) | 0.793 (0.0527) | 0.412 (0.108) | 0.791 (0.043) |
Men, n (%) | 803 (58) | 1250 (49) | 204 (58) | 1017 (58) | 698 (70) | 103 (58) | 238 (64.0) | 435 (100) | 235 (61) | 405 (50) |