Skip to main content

Table 2 Maximal responses and half maximal effective and inhibitory concentrations

From: Modulation of human airway smooth muscle biology by human adipocytes

  Carbachol Isoproterenol
EC50 (nM) Max response (%KCl) IC50 (nM) Max response (%carbachol)
Control 62 ± 38 184 ± 16 24 ± 12 2 ± 5
Intrathoracic 225 ± 110 206 ± 16 62 ± 33 0 ± 6
Extrathoracic 260 ± 62 187 ± 8 19 ± 8 −4 ± 5
  1. EC50 and IC50 for carbachol and isoproterenol ± pre-treatment with adipocyte-conditioned media. Data presented as mean ± SEM. n = 6 (donors)