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Table 2 Maximal responses and half maximal effective and inhibitory concentrations

From: Modulation of human airway smooth muscle biology by human adipocytes

 

Carbachol

Isoproterenol

EC50 (nM)

Max response (%KCl)

IC50 (nM)

Max response (%carbachol)

Control

62 ± 38

184 ± 16

24 ± 12

2 ± 5

Intrathoracic

225 ± 110

206 ± 16

62 ± 33

0 ± 6

Extrathoracic

260 ± 62

187 ± 8

19 ± 8

−4 ± 5

  1. EC50 and IC50 for carbachol and isoproterenol ± pre-treatment with adipocyte-conditioned media. Data presented as mean ± SEM. n = 6 (donors)
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Respiratory Research

ISSN: 1465-993X

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