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Table 1 Baseline characteristics of the study patients

From: Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis

Age (years)   69 (63–72)
Sex M 25 (73.5%)
  F 9 (26.5%)
Smoking History current or ex 27 (79.4%)
  never 7 (20.6%)
GAP score I 22 (64.7%)
(Stage) II 8 (23.5%)
  III 4 (11.8%)
SP-A (ng/ml)   77.0 (43.3–95.2)
SP-D (ng/ml)   217.0 (150.0–333.0)
KL-6 (U/ml)   972.0 (572.0–1440.0)
PaO2 (mmHg)   87.8 (80.7–91.6)
PaCO2 (mmHg)   40.2 (37.6–41.7)
AaDO2   12.6 (8.0–17.9)
FVC (L)   2.7 (2.1–3.2)
%FVC   93.0 (75.5–104.3)
FEV1 (L)   2.3 (1.9–2.6)
%FEV1   83.3 (76.9–88.2)
DLCO (ml/min/mmHg) 12.0 (10.1–15.4)
%DLCO   60.0 (52.4–76.1)
6MWD (m)   430 (365–480)
Minimum SpO2 (%) during 6MWT 93 (88–99)
Cell Recovery (×105/ml) 1.23 (0.65–1.67)
Cell population (%)
 Macrophages 87.4 (81.8–92.9)
 Lymphocyte 6.2 (2.7–11.8)
 Neutrophils 2.2 (1.4–3.6)
 Eosinophils 1.55 (0.4–3.1)
CD4/8 (ratio) 2.0 (1.1–2.7)
  1. n (%) or median ± IQR. DLCO, %DLCO; n = 31, other; n = 34. Definition of abbreviations: FVC Forced vital capacity, %FVC Percent predicted FVC, FEV1 Forced expiratory volume in the first second, %FEV1 Percentage of predicted FEV1, DLco Diffusing capacity of lung carbon monoxide, %DLco Percent predicted DLCO, SP-A Surfactant protein A; SP-D Surfactant protein D; KL-6 Krebs von den Lungen-6; 6MWD 6-min walk distance; 6MWT 6-min walk test