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Table 1 Baseline characteristics of the study patients

From: Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis

Age (years)

 

69 (63–72)

Sex

M

25 (73.5%)

 

F

9 (26.5%)

Smoking History

current or ex

27 (79.4%)

 

never

7 (20.6%)

GAP score

I

22 (64.7%)

(Stage)

II

8 (23.5%)

 

III

4 (11.8%)

SP-A (ng/ml)

 

77.0 (43.3–95.2)

SP-D (ng/ml)

 

217.0 (150.0–333.0)

KL-6 (U/ml)

 

972.0 (572.0–1440.0)

PaO2 (mmHg)

 

87.8 (80.7–91.6)

PaCO2 (mmHg)

 

40.2 (37.6–41.7)

AaDO2

 

12.6 (8.0–17.9)

FVC (L)

 

2.7 (2.1–3.2)

%FVC

 

93.0 (75.5–104.3)

FEV1 (L)

 

2.3 (1.9–2.6)

%FEV1

 

83.3 (76.9–88.2)

DLCO (ml/min/mmHg)

12.0 (10.1–15.4)

%DLCO

 

60.0 (52.4–76.1)

6MWD (m)

 

430 (365–480)

Minimum SpO2 (%) during 6MWT

93 (88–99)

Cell Recovery (×105/ml)

1.23 (0.65–1.67)

Cell population (%)

 Macrophages

87.4 (81.8–92.9)

 Lymphocyte

6.2 (2.7–11.8)

 Neutrophils

2.2 (1.4–3.6)

 Eosinophils

1.55 (0.4–3.1)

CD4/8 (ratio)

2.0 (1.1–2.7)

  1. n (%) or median ± IQR. DLCO, %DLCO; n = 31, other; n = 34. Definition of abbreviations: FVC Forced vital capacity, %FVC Percent predicted FVC, FEV1 Forced expiratory volume in the first second, %FEV1 Percentage of predicted FEV1, DLco Diffusing capacity of lung carbon monoxide, %DLco Percent predicted DLCO, SP-A Surfactant protein A; SP-D Surfactant protein D; KL-6 Krebs von den Lungen-6; 6MWD 6-min walk distance; 6MWT 6-min walk test
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Respiratory Research

ISSN: 1465-993X

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