Fig. 2

Impaired inflammation resolution in Cdc42-KO mice during the repair phase. a H&E staining of lung sections showing inflammatory cell infiltration around vessels and capillaries in control and KO mice, n = 4 mice per group. Scale bar, 50 μm. b ALI scores at baseline (without LPS) and on days 1, 3 and 7 after LPS-induced injury in control and KO mice, n = 4 mice per group. *P < 0.05, **P < 0.01 (Student’s t test). c Analysis of the number of infiltrating neutrophils per vessels (> 30 μm in diameter), n = 6vessels in 4 mice per group. *P < 0.05, **P < 0.01 (Student’s t test)