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Table 1 Clinical features

From: The JAK2 pathway is activated in idiopathic pulmonary fibrosis

 

Control donor subjects (n = 10)

IPF patients (n = 12)

Age (yr)

57 [38–65]

66 [58–75]

Sex (M/F)

6/4

9/3

Smoking

Never smoked/Smokers

3/7

1/11

Pack-year

25 [0–28]

26.3 [11–34]

FEV1, pred

ND

72.2 [56–96]

FVC, % pred

ND

62.2 [55–68]

TLC, % pred

ND

73.5 [45–89]

DLco, % pred

ND

42.1 [31–51]

Ground glass %

0

25 [20–39]

Honeycombing %

0

35 [25–40]

NAC (y/n)

0/10

8/4

Pirfenidone (y/n)

0/10

4/8

  1. % pred % predicted, DLco diffusion capacity of the lung for carbon monoxide, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, ND not determined, Pack-year 1 year of smoking 20 cigarettes per day, TLC total lung capacity, Ground glass % % of pulmonary parenchyma with ground glass on a computed tomography (CT) image, Honeycombing % % of pulmonary parenchyma with honeycombing on a CT image; N-acetyl-l-cysteine (NAC). Data are medians [interquartile range]