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Fig. 6 | Respiratory Research

Fig. 6

From: Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

Fig. 6

Effect of SP-A variants on airway functions after Kp infection and in response to methacholine challenge (50 mg/mL) in females. In female SP-A1 (6A2, 6A4), SP-A2 (1A0, 1A3), SP-A1/SP-A2 (6A2/1A0, co-ex), and SP-A (KO) mice, Rrs, Crs, Ers, Rn, G, and H (panel a, b, c, d, e and f)were measured after a 50 mg/mL of methacholine challenge (bar graph). Inset: depicts the effect of dose response with increasing concentrations of methacholine. Data are expressed as mean ± SD (4 replicates per group). *p < 0.05

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