Table 4 Comorbidities during the year prior to index date in (A) all patients with mild to moderate and severe asthma and in (B) patents after exclusion of concurrent COPD diagnosis. Age adjusted data presented as number (%)
A | B | |||||
|---|---|---|---|---|---|---|
Full study population | Asthma only (no COPD) | |||||
Mild to moderate (n = 17,934) | Severe (n = 790) | P-value | Mild to moderate (n = 16,142) | Severe (n = 561) | P-value | |
Respiratory related conditions | ||||||
Acute upper respiratory tract infections | 8472 (47.2) | 378 (47.8) | 0.765 | 7667 (47.5) | 271 (48.3) | 0.738 |
Rhinitis, any | 3924 (21.9) | 173 (21.9) | 1.000 | 3764 (23.3) | 133 (23.7) | 0.870 |
Chronic sinusitis | 204 (1.1) | 14 (1.8) | 0.145 | 176 (1.1) | 11 (2.0) | 0.085 |
Nasal polyps | 548 (3.1) | 42 (5.3) | 0.001 | 493 (3.1) | 33 (5.9) | <0.001 |
Acute lower respiratory infections | 4346 (24.2) | 204 (25.8) | 0.329 | 3609 (22.4) | 131 (23.3) | 0.615 |
Chronic bronchitis | 449 (2.5) | 32 (4.1) | 0.010 | 256 (1.6) | 15 (2.8) | 0.067 |
COPD | 1821 (10.2) | 171 (21.6) | <0.001 | 0 (0.0) | 0 (0.0) | 1.000 |
Influenza | 108 (0.6) | 10 (1.2) | 0.038 | 91 (0.6) | 6 (1.0) | 0.205 |
Pneumonia | 2574 (14.4) | 164 (20.7) | <0.001 | 2011 (12.5) | 93 (16.5) | 0.005 |
Other conditions | 8625 (48.1) | 392 (49.6) | 0.421 | 7143 (44.2) | 251 (44.7) | 0.852 |
Diabetes type 1 | 453 (2.5) | 18 (2.3) | 0.750 | 346 (2.1) | 13 (2.3) | 0.896 |
Diabetes type 2 | 1198 (6.7) | 54 (6.8) | 0.922 | 890 (5.5) | 34 (6.0) | 0.643 |
Arterial hypertension | 4450 (24.8) | 197 (25.0) | 0.971 | 3435 (21.3) | 117 (20.9) | 0.850 |
Ischaemic heart disease | 1332 (7.4) | 69 (8.7) | 0.195 | 903 (5.6) | 35 (6.2) | 0.576 |
Heart failure | 760 (4.2) | 47 (5.9) | 0.026 | 439 (2.7) | 17 (3.0) | 0.755 |
Malignant neoplasm | 20 (0.1) | 0 (0.0) | 0.702 | 15 (0.1) | 0 (0.0) | 0.996 |
Cerebrovascular diseases | 565 (3.2) | 29 (3.7) | 0.476 | 394 (2.4) | 15 (2.7) | 0.832 |
Anxiety and depression disorder | 3682 (20.5) | 161 (20.4) | 0.954 | 3198 (19.8) | 110 (19.6) | 0.948 |
Osteoporosis | 382 (2.1) | 22 (2.8) | 0.265 | 244 (1.5) | 10 (1.7) | 0.734 |
Inflammatory bowel disease | 607 (3.4) | 22 (2.8) | 0.415 | 526 (3.3) | 14 (2.4) | 0.377 |