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Table 4 Comorbidities during the year prior to index date in (A) all patients with mild to moderate and severe asthma and in (B) patents after exclusion of concurrent COPD diagnosis. Age adjusted data presented as number (%)

From: Prevalence and management of severe asthma in primary care: an observational cohort study in Sweden (PACEHR)

  A B
Full study population Asthma only (no COPD)
Mild to moderate (n = 17,934) Severe (n = 790) P-value Mild to moderate (n = 16,142) Severe (n = 561) P-value
Respiratory related conditions
 Acute upper respiratory tract infections 8472 (47.2) 378 (47.8) 0.765 7667 (47.5) 271 (48.3) 0.738
 Rhinitis, any 3924 (21.9) 173 (21.9) 1.000 3764 (23.3) 133 (23.7) 0.870
 Chronic sinusitis 204 (1.1) 14 (1.8) 0.145 176 (1.1) 11 (2.0) 0.085
 Nasal polyps 548 (3.1) 42 (5.3) 0.001 493 (3.1) 33 (5.9) <0.001
 Acute lower respiratory infections 4346 (24.2) 204 (25.8) 0.329 3609 (22.4) 131 (23.3) 0.615
 Chronic bronchitis 449 (2.5) 32 (4.1) 0.010 256 (1.6) 15 (2.8) 0.067
 COPD 1821 (10.2) 171 (21.6) <0.001 0 (0.0) 0 (0.0) 1.000
 Influenza 108 (0.6) 10 (1.2) 0.038 91 (0.6) 6 (1.0) 0.205
 Pneumonia 2574 (14.4) 164 (20.7) <0.001 2011 (12.5) 93 (16.5) 0.005
Other conditions 8625 (48.1) 392 (49.6) 0.421 7143 (44.2) 251 (44.7) 0.852
 Diabetes type 1 453 (2.5) 18 (2.3) 0.750 346 (2.1) 13 (2.3) 0.896
 Diabetes type 2 1198 (6.7) 54 (6.8) 0.922 890 (5.5) 34 (6.0) 0.643
 Arterial hypertension 4450 (24.8) 197 (25.0) 0.971 3435 (21.3) 117 (20.9) 0.850
 Ischaemic heart disease 1332 (7.4) 69 (8.7) 0.195 903 (5.6) 35 (6.2) 0.576
 Heart failure 760 (4.2) 47 (5.9) 0.026 439 (2.7) 17 (3.0) 0.755
 Malignant neoplasm 20 (0.1) 0 (0.0) 0.702 15 (0.1) 0 (0.0) 0.996
 Cerebrovascular diseases 565 (3.2) 29 (3.7) 0.476 394 (2.4) 15 (2.7) 0.832
 Anxiety and depression disorder 3682 (20.5) 161 (20.4) 0.954 3198 (19.8) 110 (19.6) 0.948
 Osteoporosis 382 (2.1) 22 (2.8) 0.265 244 (1.5) 10 (1.7) 0.734
 Inflammatory bowel disease 607 (3.4) 22 (2.8) 0.415 526 (3.3) 14 (2.4) 0.377