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Fig. 3 | Respiratory Research

Fig. 3

From: GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization

Fig. 3

Effects of supra-physiologic levels of GM-CSF on bronchoalveolar lavage fluid content and influenza A virus load. BAL fluid was recovered from mice at indicated time points after IAV infection and total protein (a) was measured by BCA assay, while BAL concentrations of alpha-2-macroglobulin (b) and amphiregulin (c) levels were quantitated by ELISA. The number of influenza A virus matrix protein (M1) transcripts was quantitated from whole lung by RT-PCR (d). Results shown represent three independent experiments (*p < 0.05, ***p < 0.0005)

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