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Fig. 5 | Respiratory Research

Fig. 5

From: Lack of SOCS3 increases LPS-induced murine acute lung injury through modulation of Ly6C(+) macrophages

Fig. 5

Lack of SOCS3 induced more Ly6C(+) macrophages in BAL of mice after LPS treatment. a One representative dot plot data for Ly6C+ macrophages in BAL. Macrophages were gated on F4/80(+)Ly6G(−) cells by flow cytometry. b Quantitative analysis of Ly6C(+) subtype macrophages. Data was presented as percentage Ly6C(+) of F4/80+ cells. c The number of Ly6C(+) macrophages in BAL were calculated and presented as mean ± standard error ×104. The expression of (d) CCR2 and (e) MHCII in F4/80(+) macrophages were quantitatively analyzed. #p < 0.05, ##p < 0.01 v.s. WT/PBS; * p < 0.05, **p < 0.01 v.s. WT/LPS group; @p < 0.05, @@p < 0.01 v.s. KO/PBS, n = 5

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