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Table 1 The clinical characteristics of subjects

From: Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD

 

Never-smoker (n = 17)

Smoker (n = 25)

Male/female

8/9

11/14

Age

56.2 ± 7.3

56.2 ± 5.7

BMI

26.4 ± 5.5

25.2 ± 2.9

Pack years

0

38.1 ± 13.5

Cig/day during past 6 months

0

17.1 ± 6.3

FEV1 [%] post-bronchodilator

118 ± 15.8

107 ± 12.8*

FEV1/FVC [%] post-bronchodilator

80.5 ± 6.4

77.7 ± 5.1

BAL macrophages [%]

90.2 ± 3.8

95.9 ± 2.4***

BAL lymphocytes [%]a

6.6(3, 15.4)

2(1,7.4)

BAL neutrophils [%]a

1.3 (0.6, 4.4)

0.6(0, 3.6)*

BAL eosinophils [%]a

0(0, 0.6)

0(0, 1.4)

BAL basophils [%]a

0(0, 0)

0(0, 0.4)

BAL mast cells [per 10 visual fields]

2(0, 5)

3(0, 13)

  1. Data is expressed as mean ± standard deviation and tested by using t-test.a, skew data, presented as median(range) and tested by Mann-Whitney U test; *, p < 0.05; ***, p < 0.001, compared with Never-smokers