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Fig. 6 | Respiratory Research

Fig. 6

From: Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD

Fig. 6

The proportion of CD8+ T cells in BAL increased and CD4+ T-cells decreased in Smokers compared to Never-smokers (a). Proteins from the leukocyte transendothelial migration (LTM) pathway and phagosome pathway correlated with proportion of CD8+ T-cells (b-c), as well as with the proportion of CD8+ CD69+ T-cells (e-f). Protein levels from the LTM pathway also correlated with the level of lung obstruction; FEV1/FVC (d). R2 and p-values refer to PLS inner relation

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