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Table 3 Univariable and multivariable analysis of possible predictors of the biological behavior of solitary fibrous tumors of the pleura

From: Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score – a multicenter study

Variable

Univariable analysis

Multivariable analysis

HR (95% CI)

p-value

HR (95% CI)

p-value

Tumor size ≥10 cm

8.8 (1.8–43.5)

0.008

81.8 (1.7–4016.8)

0.027

Necrosis

3.4 (0.8–14.6)

0.089

1.7 (0.1–18.4)

0.7

MIB-1 ≥ 10%

13.3 (3.6–50.7)

< 0.001

12.3 (1.1–139.5)

0.043

Mitoses ≥4/10 HPF

13.1 (1.6–112.0)

0.019

36.6 (1.2–1103.7)

0.039

Atypical location

1.6 (0.2–13.4)

0.641

  

Non-pedunculated

196.6 (0.0–126,601,532.0)

0.439

  

Pleomorphism

9.8 (2.2–44.5)

0.003

11.2 (0.6–22.3)

0.1