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Fig. 4 | Respiratory Research

Fig. 4

From: TLR3 promotes MMP-9 production in primary human airway epithelial cells through Wnt/β-catenin signaling

Fig. 4

Relocation of β-catenin after TGF-β and poly IC treatment. a Immunofluorescence analysis of β-catenin and E-cadherin expression in submerged human AEC exposed to TGF-β and/or poly(I:C) (×40). b After cellular fractionation, nuclear levels of active and total β-catenin was investigated by western blotting. c Primary AEC cultured under submerged or ALI conditions were treated with an inhibitor of PKD (CID755673) before stimulation for 24 h with TGF-β and/or poly(I:C). Levels of MMP-9 were then determined by ELISA. Data are derived from 3 independent experiments and statistical significances were determined with a one-way ANOVA followed by a Tukey’s post-hoc test

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Respiratory Research

ISSN: 1465-993X

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