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Table 4 Comparison of clinical characteristics between the response group and non-response group

From: Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study

 

Response

group (n = 42)

Non-response

group (n = 44)

p-value

*Age (year)

55.5 ± 11.3

55.8 ± 9.7

0.895

F: M

28 (66.7): 14 (33.3)

31 (70.5): 13 (29.5)

0.705

Follow-up duration (month)

36.6 ± 14.1

28.6 ± 12.2

0.006

Pulmonary function test

   

 FVC (%)

63.6 ± 17.6

79.9 ± 18.4

<0.001

 FEV1 (%)

71.7 ± 20.8

88.6 ± 19.9

<0.001

 DLco (%)

56.9 ± 19.0

70.5 ± 25.0

0.008

Resting PaO2 mm Hg

81.4 ± 17.0

92.5 ± 11.0

0.004

Smoking status

  

0.022

 Never smoker

30/40 (75.0)

32/43 (74.4)

 

 Ex-smoker

10/40 (25.0)

5/43 (11.6)

 

 current smoker

.

6/43 (14.0)

 

Smoking amount (Pys)

26.5 ± 17.2

32.4 ± 15.1

0.415

Initial symptom

   

 Dyspnea of exertion

28/35 (80.0)

30/36 (83.3)

0.717

 Cough

26/36 (72.2)

23/36 (63.9)

0.448

 Sputum

13/33 (39.4)

11/32 (34.4)

0.675

  *Duration of Symptom (month)

3.4 ± 4.4

7.1 ± 9.3

0.038

*CRP (mg/dL)

1.97 ± 5.01

1.19 ± 2.19

0.416

ANA (positive)

3/25 (12.0)

12/28 (42.9)

0.013

RF (positive)

2/25 (8.0)

8/30 (26.7)

0.092

Outcome

  

0.105

 Alive

30/42 (71.4)

36/44 (81.8)

 

 Death

.

2/44 (4.5)

 

 Follow-up loss

12/42 (28.6)

6/44 (13.6)

 
  1. Note: Values in parentheses are percentages
  2. F:M female:male, FVC forced vital capacity, % pred percentage of the predicted value, FEV 1 forced expiratory volume, DL CO diffusing capacity of the lung for carbon monoxide, PaO 2 arterial oxygen tension, CRP C-reactive protein, ANA antinuclear antibody, RF rheumatoid factor
  3. *Duration of symptoms, and CRP showed a non-normal distribution in the response group
  4. *Age, duration of symptoms, and CRP showed a non-normal distribution in the non-response group
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Respiratory Research

ISSN: 1465-993X

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