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Table 4 Comparison of clinical characteristics between the response group and non-response group

From: Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study

  Response group (n = 42) Non-response group (n = 44) p-value
*Age (year) 55.5 ± 11.3 55.8 ± 9.7 0.895
F: M 28 (66.7): 14 (33.3) 31 (70.5): 13 (29.5) 0.705
Follow-up duration (month) 36.6 ± 14.1 28.6 ± 12.2 0.006
Pulmonary function test    
 FVC (%) 63.6 ± 17.6 79.9 ± 18.4 <0.001
 FEV1 (%) 71.7 ± 20.8 88.6 ± 19.9 <0.001
 DLco (%) 56.9 ± 19.0 70.5 ± 25.0 0.008
Resting PaO2 mm Hg 81.4 ± 17.0 92.5 ± 11.0 0.004
Smoking status    0.022
 Never smoker 30/40 (75.0) 32/43 (74.4)  
 Ex-smoker 10/40 (25.0) 5/43 (11.6)  
 current smoker . 6/43 (14.0)  
Smoking amount (Pys) 26.5 ± 17.2 32.4 ± 15.1 0.415
Initial symptom    
 Dyspnea of exertion 28/35 (80.0) 30/36 (83.3) 0.717
 Cough 26/36 (72.2) 23/36 (63.9) 0.448
 Sputum 13/33 (39.4) 11/32 (34.4) 0.675
*Duration of Symptom (month) 3.4 ± 4.4 7.1 ± 9.3 0.038
*CRP (mg/dL) 1.97 ± 5.01 1.19 ± 2.19 0.416
ANA (positive) 3/25 (12.0) 12/28 (42.9) 0.013
RF (positive) 2/25 (8.0) 8/30 (26.7) 0.092
Outcome    0.105
 Alive 30/42 (71.4) 36/44 (81.8)  
 Death . 2/44 (4.5)  
 Follow-up loss 12/42 (28.6) 6/44 (13.6)  
  1. Note: Values in parentheses are percentages
  2. F:M female:male, FVC forced vital capacity, % pred percentage of the predicted value, FEV 1 forced expiratory volume, DL CO diffusing capacity of the lung for carbon monoxide, PaO 2 arterial oxygen tension, CRP C-reactive protein, ANA antinuclear antibody, RF rheumatoid factor
  3. *Duration of symptoms, and CRP showed a non-normal distribution in the response group
  4. *Age, duration of symptoms, and CRP showed a non-normal distribution in the non-response group