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Table 2 Characteristics according to treatment in patients followed-up for more than one year

From: Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study

  No treatment group (n = 9) Treatment group (n = 86) P-value
Age (year) 63.0 (57.5, 66.0) 55.0 (48.0, 64.3) 0.061
F: M 5 (55.6): 4 (44.4) 59 (68.6): 27 (31.4) 0.467
Follow-up duration (month) 23.0 (20.5, 43.0) 30.5 (20.8, 42.0) 0.412
Pulmonary function test    
 FVC (%) 83.0 (63.5, 91.0) 69.5 (58.0, 87.0) 0.291
 FEV1 (%) 100.0 (75.0, 104.5) 80.0 (64.0, 95.0) 0.111
 DLco (%) 70.5 (61.3, 79.3) 48.0 (61.0, 80.0) 0.165
*Resting PaO2 mm Hg 85.0 (76.3, 91.0) 89.0 (77.5, 98.0) 0.442
Smoking status    0.302
 Never smoker 6/9 (66.7) 62/83 (74.7)  
 Ex-smoker 1/9 (11.1) 15/83 (18.1)  
 current smoker 2/9 (22.2) 6/83 (7.2)  
Smoking amount (Pys) 30.0 (15.0, −) 30.0 (17.5, 44.0) 0.539
Initial symptom    
 Dyspnea of exertion 6/9 (66.7) 58/71 (81.7) 0.373
 Cough 6/9 (66.7) 49/72 (68.1) 1.000
 Sputum 4/6 (66.7) 24/65 (36.9) 0.204
*Duration of symptom (month) 36.0 (3.5, 55.5) 3.0 (1.0, 6.0) 0.127
*CRP (mg/dL) 0.48 (0.31, 1.87) 0.45 (0.18, 1.31) 0.407
ANA (positive) 3/6 (50.0) 15/53 (28.3) 0.357
RF (positive) 1/4 (25.0) 10/55 (18.2) 0.572
Outcome    0.303
 Alive 7/9 (77.8) 66/86 (76.7)  
 Death 1/9 (11.1) 2/86 (2.3)  
 Follow-up loss 1/9 (11.1) 18/86 (20.9)  
  1. Note: Values in parentheses are percentages
  2. F:M female:male, FVC forced vital capacity, % pred percentage of the predicted value, FEV 1 forced expiratory volume, DL CO diffusing capacity of the lung for carbon monoxide, PaO 2 arterial oxygen tension, CRP C-reactive protein, ANA antinuclear antibody, RF rheumatoid factor
  3. Note: data are expressed as the median with interquartile range or number with proportion (%)
  4. *CRP showed non-normal distribution in the no treatment group
  5. *Resting PaO2 mm Hg, duration of symptoms, and CRP showed a non-normal distribution in the treatment group