| No treatment group (n = 9) | Treatment group (n = 86) | P-value |
---|---|---|---|
Age (year) | 63.0 (57.5, 66.0) | 55.0 (48.0, 64.3) | 0.061 |
F: M | 5 (55.6): 4 (44.4) | 59 (68.6): 27 (31.4) | 0.467 |
Follow-up duration (month) | 23.0 (20.5, 43.0) | 30.5 (20.8, 42.0) | 0.412 |
Pulmonary function test | Â | Â | Â |
 FVC (%) | 83.0 (63.5, 91.0) | 69.5 (58.0, 87.0) | 0.291 |
 FEV1 (%) | 100.0 (75.0, 104.5) | 80.0 (64.0, 95.0) | 0.111 |
 DLco (%) | 70.5 (61.3, 79.3) | 48.0 (61.0, 80.0) | 0.165 |
*Resting PaO2 mm Hg | 85.0 (76.3, 91.0) | 89.0 (77.5, 98.0) | 0.442 |
Smoking status | Â | Â | 0.302 |
 Never smoker | 6/9 (66.7) | 62/83 (74.7) |  |
 Ex-smoker | 1/9 (11.1) | 15/83 (18.1) |  |
 current smoker | 2/9 (22.2) | 6/83 (7.2) |  |
Smoking amount (Pys) | 30.0 (15.0, −) | 30.0 (17.5, 44.0) | 0.539 |
Initial symptom | Â | Â | Â |
 Dyspnea of exertion | 6/9 (66.7) | 58/71 (81.7) | 0.373 |
 Cough | 6/9 (66.7) | 49/72 (68.1) | 1.000 |
 Sputum | 4/6 (66.7) | 24/65 (36.9) | 0.204 |
  *Duration of symptom (month) | 36.0 (3.5, 55.5) | 3.0 (1.0, 6.0) | 0.127 |
*CRP (mg/dL) | 0.48 (0.31, 1.87) | 0.45 (0.18, 1.31) | 0.407 |
ANA (positive) | 3/6 (50.0) | 15/53 (28.3) | 0.357 |
RF (positive) | 1/4 (25.0) | 10/55 (18.2) | 0.572 |
Outcome | Â | Â | 0.303 |
 Alive | 7/9 (77.8) | 66/86 (76.7) |  |
 Death | 1/9 (11.1) | 2/86 (2.3) |  |
 Follow-up loss | 1/9 (11.1) | 18/86 (20.9) |  |