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Table 2 Characteristics according to treatment in patients followed-up for more than one year

From: Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study

 

No treatment group (n = 9)

Treatment group (n = 86)

P-value

Age (year)

63.0 (57.5, 66.0)

55.0 (48.0, 64.3)

0.061

F: M

5 (55.6): 4 (44.4)

59 (68.6): 27 (31.4)

0.467

Follow-up duration (month)

23.0 (20.5, 43.0)

30.5 (20.8, 42.0)

0.412

Pulmonary function test

   

 FVC (%)

83.0 (63.5, 91.0)

69.5 (58.0, 87.0)

0.291

 FEV1 (%)

100.0 (75.0, 104.5)

80.0 (64.0, 95.0)

0.111

 DLco (%)

70.5 (61.3, 79.3)

48.0 (61.0, 80.0)

0.165

*Resting PaO2 mm Hg

85.0 (76.3, 91.0)

89.0 (77.5, 98.0)

0.442

Smoking status

  

0.302

 Never smoker

6/9 (66.7)

62/83 (74.7)

 

 Ex-smoker

1/9 (11.1)

15/83 (18.1)

 

 current smoker

2/9 (22.2)

6/83 (7.2)

 

Smoking amount (Pys)

30.0 (15.0, −)

30.0 (17.5, 44.0)

0.539

Initial symptom

   

 Dyspnea of exertion

6/9 (66.7)

58/71 (81.7)

0.373

 Cough

6/9 (66.7)

49/72 (68.1)

1.000

 Sputum

4/6 (66.7)

24/65 (36.9)

0.204

  *Duration of symptom (month)

36.0 (3.5, 55.5)

3.0 (1.0, 6.0)

0.127

*CRP (mg/dL)

0.48 (0.31, 1.87)

0.45 (0.18, 1.31)

0.407

ANA (positive)

3/6 (50.0)

15/53 (28.3)

0.357

RF (positive)

1/4 (25.0)

10/55 (18.2)

0.572

Outcome

  

0.303

 Alive

7/9 (77.8)

66/86 (76.7)

 

 Death

1/9 (11.1)

2/86 (2.3)

 

 Follow-up loss

1/9 (11.1)

18/86 (20.9)

 
  1. Note: Values in parentheses are percentages
  2. F:M female:male, FVC forced vital capacity, % pred percentage of the predicted value, FEV 1 forced expiratory volume, DL CO diffusing capacity of the lung for carbon monoxide, PaO 2 arterial oxygen tension, CRP C-reactive protein, ANA antinuclear antibody, RF rheumatoid factor
  3. Note: data are expressed as the median with interquartile range or number with proportion (%)
  4. *CRP showed non-normal distribution in the no treatment group
  5. *Resting PaO2 mm Hg, duration of symptoms, and CRP showed a non-normal distribution in the treatment group