Skip to main content

Table 4 Multilevel logistic regression models of the variability in adherence to good clinical practice criteria for three categories: clinical evaluation of the patient, disease evaluation and therapeutic interventions

From: Variability in adherence to clinical practice guidelines and recommendations in COPD outpatients: a multi-level, cross-sectional analysis of the EPOCONSUL study

 

Intra-class correlation (ICC)

Median Odds Ratio (MOR)

Variables

Adjusted OR (95% CI)

p

Adherence to good clinical practice criteria in clinical evaluation (≥3 criteria fulfilled)

 Empty model 1

0.36670

3.73040

   

 Model 2: center variables1

0.31866

3.26487

   

 Model 3: patient variables2

0.36831

3.74755

   

 Full model 4 (center and patient)

0.31850

3.26345

Large hospital

0.40 (0.21–0.79)

0.008

Outpatient respiratory nursing clinic available

2.47 (1.26–4.83)

0.008

Active smokers

1.32 (1.10–1.58)

0.003

Charlson index ≥3

1.35 (1.15–1.59)

< 0.001

Number of hospital admissions in the last year ≥1

6.33 (5.02–7.98)

< 0.001

GesEPOC phenotype

 Not exacerbator (reference)

  

 Exacerbator

0.79 (0.61–1.101)

0.063

 Missing

0.36 (0.29–0.44)

< 0.001

To be taken care in specialized COPD outpatient clinic)

2.10 (1.56–2.72)

< 0.001

1: included variables in the final center model: large hospital and outpatient respiratory nursing clinic available

2: included variables in the final patient model: active smokers, Charlson index ≥3, number of hospital admissions in the last year ≥1, to be taken care in specialized COPD outpatient clinic and GesEPOC phenotype exacerbator.

Adherence to good clinical practice criteria in COPD evaluation (≥4 criteria fulfilling)

 Empty model 1

0.30343

3.13266

   

 Model 2: center variables1

0.26684

2.83994

   

 Model 3: patient variables2

0.29100

3.02953

   

 Full model 4 (center and patient)

0.24413

2.67316

Respiratory ward not available (reference)

  

Respiratory ward < 20 beds

7.09 (2.53–9.90)

< 0.001

Respiratory ward ≥20 beds

3.00 (1.37–6.60)

0.006

Age ≤ 55

1.58 (1.19–2.09)

0.001

Sex (male)

0.77 (0.61–0.96)

0.022

Charlson index ≥3

0.80 (0.68–0.94)

0.008

FEV1 <  50%

1.68 (1.42–1.99)

< 0.001

Dyspnea (MRC-m)

 0–1 (reference)

  

  ≥ 2

1.39 (1.13–1.72)

0.002

 Missing

0.69 (0.51–0.93)

0.017

 Level of dyspnea not referred to

0.65 (0.49–0.86)

0.003

GesEPOC phenotype

 Non-exacerbator (reference)

  

 Exacerbator

1.16 (0.93–1.44)

0.185

 Missing

0.17 (0.14–0.21)

< 0.001

Treatment at a specialized COPD outpatient clinic

3.25 (2.49–4.23)

< 0.001

1: variables included in the final center model: in-patient respiratory clinic ≥20 present and specialized COPD outpatient clinic available.

2: variables included in the final patient model: age ≤ 55, gender (male), Charlson index ≥3, FEV1 <  50%, dyspnea, GesEPOC exacerbator phenotype and being treated in specialized COPD outpatient clinic.

Adherence to good clinical practice criteria in therapeutic intervention (≥3 criteria fulfilled)

 Empty model 1

0.52169

6.09155

   

 Model 2: center variables1

0.46935

5.08927

   

 Model 3: patient variables2

0.49994

5.64024

   

 Full model 4 (center and patient)

0.44731

4.74211

University hospital

0.26 (0.08–0.85)

0.026

Outpatient respiratory nursing clinic availability

3.69 (1.50–9.11)

0.005

Age ≤ 55

0.60 (0.42–0.86)

< 0.005

Sex (male)

0.72 (0.55–0.93)

0.014

Charlson index ≥3

1.19 (0.99–1.42)

0.062

Number of hospital admissions in the last year ≥1

1.71 (1.38–2.11)

< 0.001

GesEPOC phenotype

 Non-exacerbator (reference)

  

 Exacerbator

0.90 (0.71–1.15)

0.404

 Missing

0.36 (0.29–0.46)

< 0.001

Treatment at a specialized COPD outpatient clinic

2.61 (2.01–3.40)

<0.001

1: variables included in the final center model: university hospital and outpatient respiratory nursing clinic availability

2: variables included in the final patient model: age ≤ 55, gender (male), Charlson index ≥3, number of hospital admissions in the last year ≥1, GesEPOC exacerbator phenotype and being treated in specialized COPD outpatient clinic

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us