Table 4 Asthma patients without obesity: differences in pulmonary function between patients with and without increased FeNO (n = 224)
|  | FeNO < 25 ppb n = 167 | FeNO ≥ 25 ppb n = 57 | Unadjusted difference (95% CI)a | Adjusted difference (95% CI)a |
|---|---|---|---|---|
Lung function | ||||
 FEV1, % pred, mean (SD) | 101.5 (17.7) | 95.2 (18.7) | −6.4 (−11.8, −0.9) | −4.4 (−9.7, 0.9) |
 FVC, % pred, mean (SD) | 112.9 (17.9) | 108.5 (18.5) | −4.4 (−9.7, 1.0) | −1.6 (−6.6, 3.4) |
 FEV1/FVC, mean (SD) | 74.5 (8.0) | 72.2 (8.4) | −2.3 (−4.8, 0.1) | −1.9 (−4.4, 0.6) |
Symptoms | ||||
 Dyspnea, n (%) | 60 (36) | 18 (32) | −4.3 (−18.6, 9.9) | −1.1 (−15.4, 13.3) |
 Wheezing, n (%) | 31 (19) | 8 (14) | −4.5 (−15.4, 6.4) | −6.4 (−17.5, 4.8) |
 Coughing with mucus, n (%) | 41 (26) | 8 (14) | −10.5 (−21.8, 0.7) | −10.5 (−21.9, 1.0) |
 Coughing without mucus, n (%) | 58 (35) | 14 (26) | −10.2 (−23.6, 3.3) | −12.2 (−24.5, 0.1) |
Symptoms worsen during: | ||||
 Physical activity, n (%) | 62 (37) | 15 (26) | −10.8 (−24.5, 2.9) | −11.1 (−24.2, 2.1) |
 Dust/pollen/animal exposure, n (%) | 58 (35) | 21 (37) | 2.1 (−12.5, 16.7) | 5.5 (−8.8, 19.8) |
 Foggy weather, n (%) | 61 (37) | 17 (30) | −6.7 (−20.8, 7.4) | −2.4 (−15.6, 10.7) |
 Night, n (%) | 17 (10) | 9 (16) | 5.6 (−5.0, 16.2) | 4.4 (−6.5, 15.3) |
 Getting up in the morning, n (%) | 24 (14) | 9 (16) | 1.4 (−9.5, 12.4) | 0.7 (−9.9, 11.4) |
ICS prescription, n (%) | 83 (50) | 24 (42) | −7.6 (−22.7, 7.5) | −8.6 (−24.0, 6.7) |