Table 3 Pulmonary function, FeNO and symptoms in asthma patients with and without obesity (n = 472)
|  | BMI < 30 kg/m2 n = 224 | BMI ≥ 30 kg/m2 n = 248 | Unadjusted difference (95% CI)a | Adjusted difference (95% CI)a |
|---|---|---|---|---|
Lung function | ||||
 FEV1, % pred, mean (SD) | 99.9 (18.1) | 97.0 (17.1) | −2.9 (−6.1, 0.3) | −3.2 (−6.3, −0.03) |
 FVC, % pred, mean (SD) | 111.8 (17.9) | 107.4 (15.5) | −4.4 (−7.4, −1.4) | −4.9 (−7.8, −2.0) |
 FEV1/FVC, mean (SD) | 74.0 (8.1) | 74.9 (8.0) | 0.9 (−0.5, 2.4) | 0.5 (−0.9, 1.9) |
FeNO, ppb, mean (SD) | 21.9 (16.9) | 19.2 (13.9) | −2.7 (−5.5, 0.1) | −1.8 (−4.6, 1.0) |
Symptoms | ||||
 Dyspnea, n (%) | 78 (35) | 114 (46) | 11.1 (2.3, 20.0) | 9.5 (0.8, 18.2) |
 Wheezing, n (%) | 39 (17) | 88 (36) | 18.1 (10.3, 25.9) | 18.5 (10.8, 26.2) |
 Coughing with mucus, n (%) | 49 (22) | 56 (23) | 0.7 (−6.8, 8.3) | 0.9 (−6.5, 8.4) |
 Coughing without mucus, n (%) | 72 (32) | 78 (32) | −0.7 (−9.1, 7.8) | −2.0 (−10.4, 6.3) |
Symptoms worsen during: | ||||
 Physical activity, n (%) | 77 (34) | 121 (49) | 14.8 (6.0, 23.7) | 12.9 (4.2, 21.6) |
 Dust/pollen/animal exposure, n (%) | 79 (35) | 75 (30) | −5.0 (−13.5, 3.5) | −3.5 (−11.6, 4.5) |
 Foggy weather, n (%) | 78 (35) | 94 (38) | 3.1 (−5.6, 11.8) | 1.7 (−6.6, 9.9) |
 Night, n (%) | 26 (12) | 38 (15) | 3.7 (−2.5, 9.9) | 3.0 (−3.3, 9.3) |
 Getting up in the morning, n (%) | 33 (15) | 17 (7) | −7.9 (−13.5, −2.2) | −8.1 (−14.0, −2.2) |
ICS prescription, n (%) | 107 (48) | 123 (50) | 1.8 (−7.2, 10.9) | 2.5 (−6.7, 11.7) |