Fig. 4From: A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatmentAnalysis of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) in fibroblast mono-culture model. Quantitative analysis of band density in gelatin zymography of medium collected on culture day 21: Pro-MMP-2 (a), and active MMP-2 (b). The results represent fold changes relative to the control. Concentrations of TIMP-1 (c) and TIMP-2 (d) in medium collected on culture day 21. All data are shown as means ± SD of triplicate inserts. *p < 0.05 (Student’s t-test)Back to article page