Table 1 Clinical characteristics of study subjects

Number

12

9

13

Age, years

39.8 ± 2.5

52.6 ± 4.2

54.4 ± 3.8*

Gender, Female/Male

6/6

7/2

11/2

Inhaled corticosteroid dose, μg BDP equivalent

0

150.0 ± 105.2

2000 ± 258.2**^##

Atopy (n)

5

4

5

Receiving oral corticosteroids

0

0

4

Pre-bronchodilator FEV₁ (L)

3.4 ± 0.2

2.2 ± 0.3

1.5 ± 0.2***

Pre-bronchodilator FEV₁ of predicted value (%)

94.9 ± 2.5

82.3 ± 5.5

61.0 ± 5.5***

FEV₁/FVC (%)

88.2 ± 2.3

69.5 ± 2.0

64.5 ± 3.1***